How Long Does Mifepristone Stay in Your System?
Mifepristone is a prescription medication used in combination with misoprostol for a medical abortion during the early stages of pregnancy. Many patients ask: how long does mifepristone stay in your system? Understanding this timeline helps you know what to expect and ensures a safe recovery.
After taking mifepristone orally, it is absorbed into the bloodstream and begins blocking the hormone progesterone, which is necessary for pregnancy to continue. The medication reaches its highest concentration in the blood within about 1.5 hours, but its effects last longer because it binds strongly to progesterone receptors.
On average, mifepristone’s half-life is about 18 hours, which means it takes approximately this time for the body to eliminate half the dose. However, it can take up to 5 days for the medication to fully leave your system. Even after it is metabolized, the changes it triggers in the uterus continue, especially when followed by misoprostol.
It’s important to note that the presence of the medication in your system doesn’t mean you will feel side effects for the entire duration. Most side effects — such as cramping, bleeding, or nausea — occur within the first 24–48 hours after taking the second medication, misoprostol.
If you have any medical conditions, are breastfeeding, or are concerned about medication interactions, talk to a healthcare provider before taking mifepristone. At Médica Center FEM, we ensure safe, supervised use of the medication, with 24/7 follow-up care.
Frequently Asked Questions
1. Does mifepristone stay in the body for weeks?
No. While its effects are lasting, the medication is usually eliminated within a few days.
2. Can I drink alcohol after taking mifepristone?
It’s best to avoid alcohol for at least 48 hours to prevent dehydration and avoid masking symptoms.
3. Will mifepristone affect my future fertility?
No. When used correctly under medical supervision, mifepristone does not impact future fertility.
4. Is it safe to breastfeed after taking mifepristone?
Small amounts can pass into breast milk. Discuss timing with your doctor to ensure safety for your baby.
